T_Products

Trimethoprim is a bactericidal antibiotic effective against bacteria responsible for urinary tract infections, prostatitis, and cystitis. It is commonly combined with sulfamethoxazole to combat Staphylococcus aureus. Trimethoprim lactate is a freely soluble form of trimethoprim. GoldBio also offers Trimethoprim, which contains only the pure active ingredient, but is also less soluble.

Tripalmitoylglycerol is a triglyceride palmittic acid. It can be used to create lipid particles for drug delivery.

GoldBio Tris has the highest purity available on the market. Short for Tris (hydroxymethyl) aminomethane (THAM), Tris is an organic compound often used in buffer solutions such as TAE or TBE for electrophoresis gels. Tris is highly soluble in water and is useful in the pH range 7.0-9.0 and is also used in the preparation of Laemmli buffer, one of the most common SDS-PAGE buffers. In addition, it can also be used for many custom running and loading buffers, most often with glycine and SDS.

Tris hydrochloride is a reagent that is used for the stabilization of buffer formulations and electrophoresis of biological molecules.

Tropine is a derivative of tropane, which contains a hydroxyl group. It a a building block for the synthesis of atropine, an anticholinergic drug.

Tropolone is a bactericidal antibiotic composed of a seven-membered aromatic ring. It targets a wide variety of gram-positive and gram-negative bacteria. Tropolone has been used to prepared fused heterocycles and Ga(III) and In(III) complexes. It is also a reagent used to reduce sugars. It is freely soluble in various organic solvents.

It is suspected that tropolone targets cell membranes increasing their permeability and causing cell lysis.

Trypsin is a serine protease found in the digestive system of many vertebrates where it hydrolyzes proteins. Through trypsinisation, it cleaves peptides at the carboxyl side of arginine and lysine, unless they are followed by a proline.

Trypsin has an optimal operating pH of about 7.5-8.5 and optimal operating temperature of about 37°C. Unlike chymotrypsin, the activity of trypsin is not affected by the inhibitor tosyl phenylalanyl chloromethyl ketone (TPCK).

Trypsin is a serine protease found in the digestive system of many vertebrates where it hydrolyzes proteins. Through trypsinisation, it cleaves peptides at the carboxyl side of arginine and lysine, unless they are followed by a proline.

Trypsin has an optimal operating pH of about 7.5-8.5 and optimal operating temperature of about 37°C. Unlike chymotrypsin, the activity of trypsin is not affected by the inhibitor tosyl phenylalanyl chloromethyl ketone (TPCK).

Trypsin 1:300 indicates that one part trypsin will digest 300 parts casein in the USP activity assay.

Trypsin is a serine protease found in the digestive system of many vertebrates where it hydrolyzes proteins. Through trypsinisation, it cleaves peptides at the carboxyl side of arginine and lysine, unless they are followed by a proline.

Trypsin has an optimal operating pH of about 7.5-8.5 and optimal operating temperature of about 37°C. Unlike chymotrypsin, the activity of trypsin is not affected by the inhibitor tosyl phenylalanyl chloromethyl ketone (TPCK).

Trypsin inhibitor is a serine protease inhibitor from soybeans that is specific for trypsin and trypsin-like proteases. Trypsin inhibitor from soybeans is a monomeric protein containing 181 amino acid residues in a single polypeptide chain cross-linked by two disulfide bridges. Soybean trypsin inhibitor forms a 1:1 complex with the active protease site. Inhibition may be reversed and is pH dependent. The optimal pH for trypsin binding is 8.0.

1,2,3,4-Tetra-O-acetyl-β-D-glucuronic acid methyl ester has been used in various biochemical studies. It has been used to study the potential of water-soluble camptothecin glucuronide derivatives as a cancer prodrug monotherapy and antibody-directed enzyme prodrug therapy. Additionally, it has been used to assess the role of glycosylthio heterocycles in carbohydrates.

Tryptophol is an aromatic alcohol found as a secondary product of alcoholic fermentation that induces sleep in humans. Typically synthesized in yeasts it is also produced by the trypanosomal parasite Trypanosoma brucei resulting in sleeping sickness. Tryptophol is a possible functional analog of serotonin or melatonin and shows genotoxicity in vitro. Saccharomyces cerevisiae uses it as a quorum sensing molecule.

Tryptophol is used as a precursor to the synthesis of tryptamines like DMT and the drug indoramin along with TNF-alpha modulators. When administered to rodents it resulted in significantly depressed antibody production.

Thymic stromal lymphopoietin (TSLP) is a hemopoietic protein belonging to the cytokine family and is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. It is mainly expressed in tissues, including heart, liver and prostate. TSLP signals through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL7R alpha chain. Like IL7, TSLP induces phosphorylation of STAT3 and STAT5, but uses kinases other than the JAKs for activation. After binding STAT5, phosphorylation is induced which results in the expression of downstream transcription factors. TSLP enhances the maturation of CD11c+ dendritic cells and induces allergic inflammation by directly activating mast cells. TSLP’s expression is linked to many disease states including asthma, inflammatory arthritis, atopic dermatitis, and eczema and other allergic states but the factors which induce the activation of TSLP release are not clearly defined. Human TSLP shares approximately 43 % amino acid sequence identity with mouse TSLP.

10 x 10 cm tube floater with a capacity for 10 1.5 mL tubes and 10 .6 mL tubes.

Tylosin tartrate is a macrolide antibiotic isolated from Streptomyces fradiae. It is a mixture of tylosin A, B, C, and D tartrates effective against gram-positive bacteria and Mycoplasma species. It has been used to study protein synthesis, abscess prevention in cattle, and Mycoplasma infections.

Tyramine HCl is a monoamine derived from tyrosine. It is a catecholamine releasing agent that does not have the ability to cross the blood-brain barrier. It can be released as a false transmitter.