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Sodium taurocholate is the sodium salt of taurocholic acid, a bile acid composed of cholic acid and taurine. It has many microbiological uses, and is a well-known recipe component of MacConkey agar.

It is also often used to solubilize lipids and membrane proteins, as well as functioning as an activator during studies involving different types of lipases.

Sodium taurodeoxycholate is a bile salt that acts as a detergent and as a differentiating tool. Bile salts break down bacteria that are not native to gut, while enteric bacteria are resistant to these bactericidal effects. It can also be used for isolation of membrane proteins, including inner mitochondrial membrane proteins.

Sparfloxacin is a broad-spectrum fluoroquinolone antibiotic targeting gram-negative and gram-positive bacteria as well as Mycoplasma species. It is especially effective against bacteria responsible for respiratory tract infections such as pneumonia. Sparfloxacin also displays photosensitizing effects.

Spectinomycin is an aminocyclitol antibiotic isolated from Streptomyces spectabilis. It is effective against gram-positive and gram-negative bacteria, but most commonly used against Gonococcus species. It has also been used to monitor cell fate during leaf development and as a selection marker in plants to display successful transformation of the Spcr gene.

Spectinomycin functions by binding the 30s ribosomal subunit, inhibiting tRNA translation and protein synthesis. Resistance to this antibiotic is conferred through the aadA gene and mutated rpsE gene.

GoldBio’s antibiotic solutions are provided ready to use.

The Spectinomycin Dihydrochloride Pentahydrate EZ Pak™ is the fastest and easiest way to make a set amount of sterile spectimomycin dihydrochloride solution. The kit includes pre-weighed spectimomycin dihydrochloride powder, a sterile filter and a sterile container for the filtered solution. No need to calculate, simply add the stated amount of deionized H₂O, filter, and pour into the labeled bottle for easy usage. The EZ Pak™ includes high quality GoldBio spectimomycin dihydrochloride and the sterile solution is ready for tissue culture, bacterial media or any number of uses.

Spectinomycin is an aminocyclitol antibiotic isolated from Streptomyces spectabilis. It is effective against gram-positive and gram-negative bacteria, but most commonly used against Gonococcus species. It has also been used to monitor cell fate during leaf development and as a selection marker in plants to display successful transformation of the Spcr gene.

Spectinomycin functions by binding the 30s ribosomal subunit, inhibiting tRNA translation and protein synthesis. Resistance to this antibiotic is conferred through the aadA gene and mutated rpsE gene.

Spermidine trihydrochloride is a polyamine that inhibits neuronal nitric oxide synthase (nNOS) and binds and precipitates DNA. It may be used to purify DNA binding proteins. Additionally, spermidine stimulates T4 polynucleotide kinase activity. It is involved in growth, development, and the stress response in plants.

Spermine is a polyamine derived from spermidine. It is involved in the cellular metabolism of all eukaryotic cells, as well as being vital to some bacteria.

Due to its polycationic nature, nonviral gene therapy applications involving spermine have shown promising results. This has had a positive impact in cancer research involving the lungs.

Gene transfer within the lungs is met with many obstacles due to inflammatory and immunological responses. Using spermine as a gene delivery vehicle to transfect living cells has bypassed some of these obstacles, showing higher gene expression.

Spermine tetrahydrochloride is used to precipitate DNA from low salt aqueous buffers. In the neurological system it exhibits neuroprotective effects at high concentrations and neurotoxicity at lower concentrations. Spermine itself can also act as a regulator of gene expression and a cell and DNA damage inhibitor by scavenging free radicals.

Spiramycin is a broad-spectrum macrolide antibiotic effective against gram-negative and gram-positive bacteria as well as some Toxoplasma parasites. Spiramycin is a mixture of spiramycin I, II, and III and has been used to study sepsis in mice.

Streptavidin Agarose Resin is a high affinity biotin-binding chromatography resin with streptavidin covalently bound to 6% crosslinked agarose beads and a biotin binding capacity of >120 nmol/ml of gel. Immobilized Streptavidin resin is suitable for gravity flow columns, spin columns, and FPLC methods. Immobilized Streptavidin can be used for affinity chromatography purifications by separating biotinylated proteins from nonbiotinylated proteins and for affinity purification of antigens when used with biotinylated antibodies.

Streptomycin is an aminoglycoside antibiotic primarily effective against gram-negative bacteria and Mycobacterium species. It is commonly used in cell culture media to prevent bacterial contamination. It has also been used to precipitate nucleic acids during protein purification techniques and to study mechanisms of Streptomycin resistance.

Streptomycin is an aminoglycoside antibiotic primarily effective against gram-negative bacteria and Mycobacterium species. It is commonly used in cell culture media to prevent bacterial contamination. It has also been used to precipitate nucleic acids during protein purification techniques and to study mechanisms of Streptomycin resistance.

GoldBio’s antibiotic solutions are provided ready to use.

The Streptomycin Sulfate EZ Pak™ is the fastest and easiest way to make a set amount of sterile streptomycin sulfate solution. The kit includes pre-weighed streptomycin sulfate powder, a sterile filter and a sterile container for the filtered solution. No need to calculate, simply add the stated amount of deionized H₂O, filter, and pour into the labeled bottle for easy usage. The EZ Pak™ includes high-quality GoldBio streptomycin sulfate, and the sterile solution is ready for tissue culture, bacterial media or any number of uses.

Streptozocin is an anti-tumor agent reserved as a last resort against metastatic pancreatic islet cells. Streptozocin functions by adding methyl and alkyl groups to DNA and interfering with normal base pairing. This damages the DNA and causes a decrease in tumor size. Streptozocin enters cells via the glucose transport protein, GLUT2. It is capable of causing vasorelaxation, NCOAT inhibition, and donating nitric oxide (NO).

Sulbactam is a β-lactamase inhibitor useful in combination with β-lactam antibiotics to increase their potency. It irreversibly inactivates β-lactamase enzymes, preventing them from degrading β-lactam antibiotics. Sulbactam has been used in combination with ampicillin and cefoperazone to inhibit β-lactamase enzymes during Agrobacterium-mediated plant genetic modifications. It may also be used in cell signaling studies.

Sulbactam is a β-lactamase inhibitor useful in combination with β-lactam antibiotics to increase their potency. It irreversibly inactivates β-lactamase enzymes, preventing them from degrading β-lactam antibiotics. Sulbactam has been used in combination with ampicillin and cefoperazone to inhibit β-lactamase enzymes during Agrobacterium-mediated plant genetic modifications. It may also be used in cell signaling studies. Sulbactam sodium is freely soluble in aqueous solution.

Sulfadoxine is a broad-spectrum sulfonamide antibiotic effective against gram-negative and gram-positive bacteria. It is commonly used against malaria, especially Plasmodium falciparum malaria with chloroquine resistance. It has been used to study Toxoplasma gondii infections and to prevent infections in post-surgical animal models.

Sulfamethazine is broad-spectrum sulfonamide antibiotic targeting bacteria causing bronchitis and urinary tract infections. It is used in disposition and depletion studies of kinetics and to develop procedures used for quantification. Sulfamethazine is also an inducer of CYP3A4.