PDGF & VEGF
PDGFAA (dimer), Rat
Catalog ID | Size | Pricing | |
---|---|---|---|
1550-14-10 | 10 μg | $ 170.00 | |
1550-14-100 | 100 μg | $ 933.00 | |
1550-14-500 | 500 μg | $ 1,905.00 |
Description
Platelet-derived growth factor (PDGF) is a glycoprotein present in serum but absent from plasma. PDGF has three subforms: PDGFAA, PDGFBB, and PDGF-AB. This form is a disulfide-linked homodimer consisting of two peptide chains A (PDGFAA). It is involved in a number of biological processes, including hyperplasia, embryonic neuron development, chemotaxis, and respiratory tubule epithelial cell development. The function of PDGF is mediated by two tyrosine kinase receptors, PDGFR-α and PDGFR-β. PDGFR-α is the receptor that binds PDGFAA.
Sterile Filtered White lyophilized powder. Purified and tested for use in cell culture.
Product Specifications
Catalog ID | 1550-14 |
---|---|
MW | ~25.3 kDa |
Storage/Handling | Store desiccated at -20°C. |
PDGFBB (dimer), Human
Catalog ID | Size | Pricing | |
---|---|---|---|
1150-10-10 | 10 μg | $ 170.00 | |
1150-10-100 | 100 μg | $ 593.00 | |
1150-10-500 | 500 μg | $ 1,627.00 |
Description
Platelet-derived growth factor (PDGF) is a glycoprotein present in serum but absent from plasma. PDGF has three subforms: PDGFAA, PDGFBB, and PDGF-AB. This form is a disulfide-linked homodimer consisting of two peptide chains B (PDGFBB). It is involved in a number of biological processes, including hyperplasia, embryonic neuron development, chemotaxis, and respiratory tubule epithelial cell development. In contrast to PDGFAA, the beta chains in PDGFBB are sufficient for mitogenesis. The function of PDGF is mediated by two tyrosine kinase receptors, PDGFR-α and PDGFR-β, both of which bind PDGFBB.
Product Specifications
Catalog ID | 1150-10 |
---|---|
MW | ~24.8 kDa |
Storage/Handling | Store desiccated at -20°C. |
VEGF120, Murine
Catalog ID | Size | Pricing | |
---|---|---|---|
1350-06-10 | 10 μg | $ 170.00 | |
1350-06-100 | 100 μg | $ 933.00 | |
1350-06-500 | 500 μg | $ 1,905.00 |
Description
Vascular Endothelial Growth Factor is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays a prominent role in normal and pathological angiogenesis. VEGF has been implicated in the induction of tumor metastasis, intra-ocular neovascular syndromes and angiogenesis. Three mouse cDNA clones (monomeric VEGF having 120, 164 or 188 amino acids) have been identified through alternative splicing. Two receptor tyrosine kinases (RTKs), Flt-1 and Flk-1 (the mouse homologue of human KDR) have been shown to bind VEGF with high affinity.
Product Specifications
Catalog ID | 1350-06 |
---|---|
MW | ~28.4 kDa |
Storage/Handling | Store desiccated at -20°C. |
VEGF164, Murine
Catalog ID | Size | Pricing | |
---|---|---|---|
1350-07-10 | 10 μg | $ 170.00 | |
1350-07-100 | 100 μg | $ 933.00 | |
1350-07-500 | 500 μg | $ 1,905.00 |
Description
Vascular Endothelial Growth Factor is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays a prominent role in normal and pathological angiogenesis. VEGF has been implicated in the induction of tumor metastasis, intra-ocular neovascular syndromes and angiogenesis. Three mouse cDNA clones (monomeric VEGF having 120, 164 or 188 amino acids) have been identified through alternative splicing. Two receptor tyrosine kinases (RTKs), Flt-1 and Flk-1 (the mouse homologue of human KDR) have been shown to bind VEGF with high affinity.
Product Specifications
Catalog ID | 1350-07 |
---|---|
MW | ~38.8 kDa |
Storage/Handling | Store desiccated at -20°C. |
VEGF164, Rat
Catalog ID | Size | Pricing | |
---|---|---|---|
1550-07-10 | 10 μg | $ 170.00 | |
1550-07-100 | 100 μg | $ 933.00 | |
1550-07-500 | 500 μg | $ 1,905.00 |
Description
Vascular endothelial growth factor is a potent growth factor and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells and promotes angiogenesis and vascular permeability. VEGF is expressed in vascularized tissues and plays a prominent role in normal and pathological angiogenesis. VEGF has been implicated in the induction of tumor metastasis, intra-ocular neovascular syndromes and angiogenesis. Two receptor tyrosine kinases (RTKs), Flt-1 and Flk-1 have been shown to bind VEGF with high affinity.
Product Specifications
Catalog ID | 1550-07 |
---|---|
MW | ~38.2 kDa |
Storage/Handling | Store desiccated at -20°C. |