M_Products

Sensitive fluorogenic substrate for fluorometric and UV-spectrophotometric assays of phosphatases.

4-Methylumbelliferyl phosphate (MUP) is a sensitive fluorogenic substrate for fluorometric and UV-spectrophotometric assays of phosphatase.

Phosphotase activity has long been studied due to its importance in cellular function. Upon dephosphorylation, MUP yields fluorescent 4-methylumelliferone (4-MU). This reaction has been used to spot PCR amplified products in ELISA and to classify bacteria.

More specifically, MUP can act as an indicator of C. perfringens because of its ability to detect phosphatase which is a highly specific indicator of C. perfringens.

4-MU-beta-D-GlcNAc (4-Methylumbelliferyl-2- acetamido-2-deoxy- β- glucopyranoside) is used as a fluorogenic substrate for N-Acetyl-beta-D-glucosaminidase (NAGase), yielding a blue fluorescent solution.

NAGase is an enzyme abundantly found in the renal tubular epithelia. Increased amounts of this enzyme in urine is often associated with various renal diseases. Therefore, interest in measuring its activity using 4-Methylumbelliferyl-2- acetamido-2-deoxy- β- glucopyranoside in order to diagnose renal diseases has grown more popular.

4-Methylumbelliferyl-alpha-L-arabinofuranoside is a substrate used in alpha-L-furanosidase.

4-Methylumbelliferyl-beta-D-galactopyranoside-6-sulfate is a fluorogenic substrate for galactose-6-sulfate sulphatase and diagnosis of Morquio disease.

4-Methylumbelliferyl-beta-D-xylopyranoside is a fluorogenic substrate used to identify beta-D-xylosidase and for Enterobacteriaceae family identification.

4-Methylumbelliferyl-beta-L-fucopyranoside is a substrate for beta-L-fucosidase and yields a blue fluorescent solution upon cleavage.

4-Methylumbelliferyl-N,N-diacetyl-beta-D-chitobioside is a fluorogenic substrate for phosphatases.

4-Methylumbelliferyl-N- acetyl-β-D- galactoside is a fluorogenic substrate for N-acetyl-beta-D-galactosaminidase and can be used for the detection of Candida albicans.

4-Methylumbelliferyl-α- L-iduronic acid cyclohexylammonium salt is a fluorogenic soluble enzyme substrate for α-L-iduronidase. α-L-iduronidase is deficient in the genetic disorder Mucopolysaccharidosis type I, also called Hurler syndrome. 4-Methylumbelliferyl-α-L-iduronide is used in the diagnosis of Hurler syndrome as the substrate in an enzymatic assay of α-L-iduronidase activity.

4-Methylumbelliferyl-α-D-glucopyranoside is a fluorogenic substrate for the identification, characterization and kinetic analysis of α-glucosidase activity. It is routinely used as a substrate for the assay of acid α-glucosidase in the diagnosis of Pompe's disease.

4-Methylumbelliferyl-β-D-cellobioside acts as a fluorogenic substrate used to measure the activity of (1,4)-β-Glucanase.

(1,4)-β-Glucanase is an enzyme that breaks down glucose by disrupting the glycosidic bonds. This enzyme is also involved in the cell wall synthesis for various fungi.

4-Methylumbelliferyl-β-D-cellobioside can also be used in Cel D Fusion screenings and activity staining in polyacrylamide gels, yielding blue fluorescence as a result.

Fluorogenic substrate for β-D-galactosidase, yielding a blue fluorescent solution upon cleavage.

4-Methylumbelliferyl-β- D-mannopyranoside is a fluorogenic substrate for detection of β-D-mannopyranosidase.

5-Methoxy-2-methylindole is a reagent useful in a variety of procedures, including: palladium acetate catalyzed arylation reactions, enantioselective Friedel-Crafts alkylations, alkylindole synthesis, and cyclopentaindolone synthesis.