Cephalosporins

Celphalosporins are a class of β-lactam antibiotics. β-lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBPs are enzymes that catalyze a pentaglycine cross-link between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine cross-link, the integrity of the cell wall is severely compromised, and ultimately leads to cell lysis and death. First generation cephalosporins are typically active against gram-positive bacteria with successive generations having an increasingly broadened activity against gram-negative bacteria. GoldBio’s catalog of cephalosporins contains antibiotics across four generations of cephalosporin activity. Cephalosporins are historically inactive against Listeria, Atypicals (including Mycoplasma and Chlamydia), MRSA, and Enterococci.
Showing 1-20 of 38 items.

Cefaclor

Catalog ID Size Pricing
C-530-500 500 mg $ 80.00
C-530-1 1 g $ 152.00

Description

Cefaclor is a second generation cephalosporin antibiotic isolated from the Acremonium fungus. It targets a wide variety of bacteria including Streptococcus pneumoniae and Haemophilus influenzae and a variety of other gram-negative and gram-positive bacteria. In addition, cefaclor has been useful in studying urinary tract and intra-abdominal infections and the mechanisms of renal transporters hOTA1, hPEPT1, and hPEPT2.

Product Specifications

Catalog ID C-530
CAS # 53994-73-3
MW 367.81 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at room temperature.
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C-530-500 2-3 Weeks 500 mg $ 80.00
C-530-1 2-3 Weeks 1 g $ 152.00

Cefadroxil

Catalog ID Size Pricing
C-540-1 1 g $ 74.00
C-540-5 5 g $ 181.00

Description

Cefadroxil is a first generation cephalosporin antibiotic with a structure similar to that of cephalexin and cephradine. It targets a wide variety of bacterial species including Staphylococcus and Streptococcus species.

Product Specifications

Catalog ID C-540
CAS # 50370-12-2
MW 363.39 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at room temperature.
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C-540-1 2-3 Weeks 1 g $ 74.00
C-540-5 2-3 Weeks 5 g $ 181.00

Cefamandole Nafate

Catalog ID Size Pricing
C-560-5 5 g $ 296.00
C-560-10 10 g $ 541.00

Description

Cefamandole nafate is a second generation cephalosporin antibiotic. It is effective against a variety of gram-negative and gram-positive bacteria. It has been used to study the expression and inhibition of the penicillin binding proteins, especially PBP 2A. Cefamandole nafate is freely soluble in aqueous solution and methanol.

Product Specifications

Catalog ID C-560
CAS # 42540-40-9
MW 512.49 g/mol
Grade MOLECULAR BIOLOGY GRADE
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C-560-5 2-3 Weeks 5 g $ 296.00
C-560-10 2-3 Weeks 10 g $ 541.00

Cefamandole Sodium Salt

Catalog ID Size Pricing
C-561-100 100 mg $ 169.00
C-561-500 500 mg $ 632.00

Description

Cefamandole sodium salt is a second generation cephalosporin antibiotic. It is effective against a variety of gram-negative and gram-positive bacteria. It has been used to study the expression and inhibition of the penicillin binding proteins, especially PBP 2A. Cefamandole sodium salt is freely soluble in aqueous solution.

Product Specifications

Catalog ID C-561
CAS # 30034-03-8
MW 484.48 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at 4°C.
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C-561-100 2-3 Weeks 100 mg $ 169.00
C-561-500 2-3 Weeks 500 mg $ 632.00

Cefdinir

Catalog ID Size Pricing
C-580-1 1 g $ 138.00
C-580-5 5 g $ 446.00
C-580-10 10 g $ 804.00

Description

Cefdinir is a third generation cephalosporin antibiotic with resistance to many β-lactamase enzymes. It is effective against gram-positive and gram-negative bacteria. Cefdinir has been used to study infections caused by Staphylococcus aureus and Neisseria gonorrhoeae as well as ftsl gene transfer in H. influenzae. It is an inhibitor of neutrophil myeloperoxidases and exhibits structural similarity to cefixime.

Product Specifications

Catalog ID C-580
CAS # 91832-40-5
MW 395.42 g/mol
Grade MOLECULAR BIOLOGY GRADE
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C-580-1 2-3 Weeks 1 g $ 138.00
C-580-5 2-3 Weeks 5 g $ 446.00
C-580-10 2-3 Weeks 10 g $ 804.00

Cefditoren pivoxil

Catalog ID Size Pricing
C-515-1 1 g $ 141.00

Description

Cefditoren pivoxil is a β-lactam, cephalosporin antibiotic that has shown to be effective against an array of gram positive and negative bacteria. In vitro studies have exhibited cefditoren pixovil to have strong activity towards methicillin and penicillin-susceptible pathogens as well as penicillin-resistant Streptococcus pneumoniae.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporin compounds are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications

Catalog ID C-515
CAS # 117467-28-4
MW 620.72 g/mol
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C-515-1 2-3 Weeks 1 g $ 141.00

Cefditoren sodium

Catalog ID Size Pricing
C-925-1 1 g $ 136.00

Description

Cefditoren sodium is sodium salt of a β-lactam cephalosporin antibiotic that disrupts peptidoglycan synthesis of bacterial cell walls. Cefditoren sodium has been used in comparative studies to ascertain effectiveness of newly synthesized antibiotics as well as in vitro testing of antibiotic resistance in bacteria.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications

Catalog ID C-925
CAS # 104146-53-4
MW 528.56 g/mol
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Packs & Pricing
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C-925-1 2-3 Weeks 1 g $ 136.00

Cefepime

Catalog ID Size Pricing
C-610-10 10 mg $ 152.00
C-610-50 50 mg $ 582.00
C-610-100 100 mg $ 1,025.00

Description

Cefepime is a fourth generation cephalosporin antibiotic effective against gram-negative and gram-positive bacteria. It is resistant to a variety of β-lactamases, and is effective against some naturally resistant bacterial species such as Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae. Cefepime is slightly soluble in aqueous solution.

Product Specifications

Catalog ID C-610
CAS # 88040-23-7
MW 480.56 g/mol
Grade MOLECULAR BIOLOGY GRADE
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C-610-10 2-3 Weeks 10 mg $ 152.00
C-610-50 In stock 50 mg $ 582.00
C-610-100 2-3 Weeks 100 mg $ 1,025.00

Cefepime HCl

Catalog ID Size Pricing
C-611-100 100 mg $ 338.00

Description

Cefepime is a fourth generation cephalosporin antibiotic effective against gram-negative and gram-positive bacteria. It is resistant to a variety of β-lactamases, and is effective against some naturally resistant bacterial species such as Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae. Cefepime HCl is more soluble compared to the pure Cefepime. Both forms have similar potencies and both are suitable for microbiology use. However, Cefepime HCl can be easier to work with because of its higher aqueous solubility.

Product Specifications

Catalog ID C-611
CAS # 123171-59-5
MW 571.50 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at -20°C.
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C-611-100 2-3 Weeks 100 mg $ 338.00

Cefixime Trihydrate

Catalog ID Size Pricing
C-620-100 100 mg $ 116.00

Description

Cefixime trihydrate is a broad-spectrum third generation cephalosporin targeting a wide range of gram-positive and gram-negative organisms. It is also used to detect ytterbium in mineral probes.

Product Specifications

Catalog ID C-620
CAS # 125110-14-7
MW 507.50 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store desiccated at 4°C. Protect from light and air. Store under inert gas.
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C-620-100 2-3 Weeks 100 mg $ 116.00

Cefmetazole free acid

Catalog ID Size Pricing
C-225-1 1 g $ 103.00
C-225-5 5 g $ 343.00

Description

Cefmetazole free acid is a second generation cephalosporin antibiotic that has a broad range of activity against gram-negative and gram-positive bacterium. Cefmetazole has exhibited great bactericidal activity against Staphylococcus aureus, which includes some methicillin-resistant strains.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications

Catalog ID C-225
CAS # 56796-20-4
MW 471.53 g/mol
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Packs & Pricing
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C-225-1 2-3 Weeks 1 g $ 103.00
C-225-5 2-3 Weeks 5 g $ 343.00

Cefmetazole Sodium

Catalog ID Size Pricing
C-631-1 1 g $ 108.00
C-631-5 5 g $ 383.00

Description

Cefmetazole is a semisynthetic second generation cephalosporin antibiotic derived from cephamycin. It is effective against a variety of gram-negative and gram-positive bacteria, exhibiting more efficacy against many gram-negative enteric bacteria than many first generation cephalosporins. In addition, cefmetazole has been used to research its effect on the expression and inhibition of the penicillin binding proteins, especially PBP2 and PBP4.

Product Specifications

Catalog ID C-631
CAS # 56796-39-5
MW 493.52 g/mol
Grade MOLECULAR BIOLOGY GRADE
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C-631-1 2-3 Weeks 1 g $ 108.00
C-631-5 2-3 Weeks 5 g $ 383.00

Cefoperazone Sodium, USP Grade

Catalog ID Size Pricing
C-660-1 1 g $ 49.00
C-660-5 5 g $ 169.00
C-660-25 5 x 5 g $ 509.00

Description

Cefoperazone is a third generation cephalosporin antibiotic primarily targeting P. aeruginosa and other gram-negative bacteria. It has also been used to study penicillin binding proteins (PBPs) and is a β-lactamase inhibitor. Cefoperazone sodium is freely soluble in aqueous solution.

Product Specifications

Catalog ID C-660
CAS # 62893-20-3
MW 667.65 g/mol
Storage/Handling Store at 4°C.
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Packs & Pricing
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C-660-1 In stock 1 g $ 49.00
C-660-5 In stock 5 g $ 169.00
C-660-25 In stock 5 x 5 g $ 509.00

Cefotaxime (Sodium) 100 mg/mL Solution

Catalog ID Size Pricing
C-104-SL10 10 mL $ 65.00
C-104-SL50 50 mL $ 155.00
C-104-SL100 100 mL $ 249.00

Description

Cefotaxime is a third generation, broad-spectrum cephalosporin antibiotic effective against various gram-negative and gram-positive bacteria. However, unlike many other cephalosporins, cefotaxime is not effective against Pseudomonas aeruginosa bacteria. Cefotaxime is often used in Agrobacterium tumefaciens-mediated transformations to regulate bacterial growth. It has been shown to exhibit a synergistic effect with Vancomycin in certain conditions.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications

Catalog ID C-104-SL
CAS # 64485-93-4
MW 477.45 g/mol
Grade MOLECULAR BIOLOGY GRADE
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Packs & Pricing
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C-104-SL10 In stock 10 mL $ 65.00
C-104-SL50 In stock 50 mL $ 155.00
C-104-SL100 In stock 100 mL $ 249.00

Cefotaxime (Sodium) 250 mg/mL Solution

Catalog ID Size Pricing
C-104-SX100 100 mL $ 489.00

Description

Cefotaxime is a third generation, broad-spectrum cephalosporin antibiotic effective against various gram-negative and gram-positive bacteria. However, unlike many other cephalosporins, cefotaxime is not effective against Pseudomonas aeruginosa bacteria. Cefotaxime is often used in Agrobacterium tumefaciens-mediated transformations to regulate bacterial growth. It has been shown to exhibit a synergistic effect with Vancomycin in certain conditions.

GoldBio’s antibiotic solutions are provided ready to use.

Product Specifications

Catalog ID C-104-SX
CAS # 64485-93-4
MW 477.45 g/mol
Grade MOLECULAR BIOLOGY GRADE
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Packs & Pricing
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C-104-SX100 In stock 100 mL $ 489.00

Cefotaxime (Sodium) EZ Pak™ for 100 mg/mL Solution

Catalog ID Size Pricing
C-104-EZ10 10 mL $ 89.00
C-104-EZ50 50 mL $ 155.00
C-104-EZ100 100 mL $ 249.00

Description

The Cefotaxime (Sodium) EZ Pak™ is the fastest and easiest way to make a set amount of sterile cefotaxime (sodium) solution. The kit includes pre-weighed cefotaxime (sodium) powder, a sterile filter and a sterile container for the filtered solution. No need to calculate, simply add the stated amount of deionized H2O, filter, and pour into the labeled bottle for easy usage. The EZ Pak™ includes high quality GoldBio cefotaxime (sodium) and the sterile solution is ready for tissue culture, bacterial media or any number of uses.

Product Specifications

Catalog ID C-104-EZ
CAS # 64485-93-4
MW 477.45 g/mol
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Packs & Pricing
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C-104-EZ10 In stock 10 mL $ 89.00
C-104-EZ50 In stock 50 mL $ 155.00
C-104-EZ100 In stock 100 mL $ 249.00

Cefotaxime (Sodium), USP Grade

Catalog ID Size Pricing
C-104-1 1 g $ 35.00
C-104-5 5 g $ 59.00
C-104-25 25 g $ 219.00

Description

Cefotaxime is a third generation, broad-spectrum cephalosporin antibiotic effective against various gram-negative and gram-positive bacteria. However, unlike many other cephalosporins, cefotaxime is not effective against Pseudomonas aeruginosa bacteria. Cefotaxime is often used in Agrobacterium tumefaciens-mediated transformations to regulate bacterial growth. It has been shown to exhibit a synergistic effect with Vancomycin in certain conditions.

Product Specifications

Catalog ID C-104
CAS # 64485-93-4
MW 477.45 g/mol
Storage/Handling Store desiccated at -20°C.
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Packs & Pricing
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C-104-1 In stock 1 g $ 35.00
C-104-5 In stock 5 g $ 59.00
C-104-25 In stock 25 g $ 219.00

Cefotetan disodium

Catalog ID Size Pricing
C-715-100 100 mg $ 92.00
C-715-1 1 g $ 668.00

Description

Cefotetan disodium is a semi-synthetic β-lactam antibiotic that is classified as a second generation cephalosporin. Cefotetan disodium effects a broad range of gram positive and gram negative bacteria. It has also displayed a significant degree of bactericidal activity towards aerobic and anaerobic bacteria.

Cephalosporins are a type of β-lactam antibiotic consisting of a four-membered β-lactam ring bound to a six-membered dihydrothiazine ring. This two-ring system causes distortion of the β-lactam amide bond, resulting in decreased resonance stabilization and increased reactivity. β-lactams inhibit the formation of peptidoglycan cross-links within bacterial cell walls by targeting penicillin-binding proteins or PBPs. Consequently, the bacterial cell wall becomes weak and cytolysis occurs. Cephalosporins are less susceptible to β-lactamases than the penicillin β-lactam antibiotics.

Antibiotics are often used in clinical in vitro tests known as antimicrobial susceptibility tests or ASTs to determine their efficacy against certain bacterial species. They are tested against gram-negative and gram-positive bacteria using panels, discs, and MIC strips by medical microbiologists. ASTs decrease the risk of using an antibiotic against bacteria exhibiting resistance to it, and the results are used in clinical settings to determine which antibiotic(s) to prescribe for various infections.

Product Specifications

Catalog ID C-715
CAS # 74356-00-6
MW 619.58 g/mol
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Packs & Pricing
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C-715-100 2-3 Weeks 100 mg $ 92.00
C-715-1 2-3 Weeks 1 g $ 668.00

Cefotiam HCl

Catalog ID Size Pricing
C-681-50 50 mg $ 162.00
C-681-100 100 mg $ 288.00

Description

Cefotiam is a second generation cephalosporin antibiotic effective against gram-negative and gram-positive bacteria. However, it is not effective against Pseudomonas aeruginosa. Cefotiam has been used as a prophylactic antibiotic against methicillin-resistant Staphylococcus aureus or MRSA. It is soluble in aqueous solution.

Product Specifications

Catalog ID C-681
CAS # 66309-69-1
MW 562.09 g/mol
Grade MOLECULAR BIOLOGY GRADE
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Packs & Pricing
,
C-681-50 2-3 Weeks 50 mg $ 162.00
C-681-100 2-3 Weeks 100 mg $ 288.00

Cefoxitin

Catalog ID Size Pricing
C-960-1 1 g $ 161.00

Description

Cefoxitin is a cephamycin antibiotic grouped with the second generation cephalosporins. It is effective against gram-positive and gram-negative bacteria and is especially effective against anaerobic bacteria. Cefoxitin is resistant to degradation by β-lactamases.

Product Specifications

Catalog ID C-960
CAS # 35607-66-0
MW 427.45 g/mol
Grade MOLECULAR BIOLOGY GRADE
Storage/Handling Store at -20°C.
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C-960-1 2-3 Weeks 1 g $ 161.00

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